Camanche (originally, Limerick; also, Clay's Bar)[3] is a former settlement in Calaveras County, California, United States.

Located at an elevation of 220 feet (67 m), the town was once called Limerick, before it was renamed to Camanche in 1849.

Gold mining at nearby Cat Camp, Poverty Bar, and Sand Hill brought its population to a peak of 1,500.

Mokelumne River water was brought in by Lancha Plana and Poverty Bar Ditch.

Buhach, an insect powder made from a plant, was manufactured on the nearby Hill Ranch.