Cambodia competed at the 2012 Summer Paralympics in London, United Kingdom, from August 29 to September 9.

The country is fielding its smallest delegation to date: a single athlete, female sprinter Thin Seng Hon.

As no Cambodian athlete qualified for the Games, the country received a wildcard invitation to send one competitor in track and field events.

[1] Thin "was born without a fully formed right leg", and uses a "$2 500 J-shaped running blade" prosthetic.

Her coach, pointing out that her prosthetic is "not custom-built for sprinting and is less comfortable and shock absorbent than those owned by her first world rivals", has argued she is likely to be disadvantaged by a "technology gap", as well as by poverty; Thin "trains on a dirt track and balances running with a full-time job at a souvenir shop".