Cambridge is a city in Cowley County, Kansas, United States.

When the Kansas City, Lawrence & Southern Railroad was built a mile south of Lazette, a new site was organized by Benjamin H. Clover and plotted on May 3, 1880 and it was named Cambridge after Cambridge University, in England.

[7] Cambridge was a station and shipping point on the Atchison, Topeka and Santa Fe Railway.

[8] The Cambridge Public Emergency Radio Tower was mooted as the location for one of two "control stations" of the Decision Information Distribution System, which would be used to alert the public of an enemy attack (the other was to have been in Ault, Colorado.)

According to the United States Census Bureau, the city has a total area of 0.17 square miles (0.44 km2), all of it land.

The climate in this area is characterized by hot, humid summers and generally mild to cool winters.

[10] The 2020 United States census counted 92 people, 43 households, and 34 families in Cambridge.

16.3% of households consisted of individuals and 4.7% had someone living alone who was 65 years of age or older.

28.2% of all households were made up of individuals, and 12.8% had someone living alone who was 65 years of age or older.

The racial makeup of the city was 95.15% White, 0.97% African American, and 3.88% from two or more races.

There were 20.0% of families and 21.9% of the population living below the poverty line, including 47.1% of under eighteens and 42.9% of those over 64.

The community is served by Central USD 462 public school district.