Cambridge City is a town in Jackson Township, Wayne County, in the U.S. state of Indiana.

[7] Cambridge City experienced growth when the Whitewater Canal was extended to that point in 1846.

[8] Situated along the historic National Road (U.S. Route 40), Cambridge City is currently a prominent destination for antique seekers.

[citation needed] The Cambridge City Historic District, Conklin-Montgomery House, and Lackey-Overbeck House are listed on the National Register of Historic Places.

29.2% of all households were made up of individuals, and 12.6% had someone living alone who was 65 years of age or older.

29.6% of all households were made up of individuals, and 16.6% had someone living alone who was 65 years of age or older.

The town celebrates its history and heritage during the second weekend in each September during the annual Canal Days festival, which commemorates the importance of the Whitewater Canal to the formation and growth of Cambridge City in the 19th century.

[14] Just south of I-70, Cambridge City is home to the Indiana Gateway Industrial Park which is home to Taconic Biosciences, Dot Foods and Sugar Creek Packaging Co. (replacing Really Cool Foods which closed in December 2011).