The new London Overground line names and colours were introduced across the London rail network in November 2024 The station was opened on 27 May 1872 by the Great Eastern Railway (GER) as part of a more direct route to Enfield Town which before opening was accessed via Angel Road station.

In 1894, with increasing traffic, the GER opened two additional tracks on the eastern side, which are known as the Fast Lines today, to allow longer distance trains to bypass the station.

[11][12] As of November 2018, the station will take part in a "pay by face" facial technology trial called "Gateless Gatelines".

[13] In the three-month data-gathering exercise 3D mapping "stereoscopic depth sensors" resembling ceiling-mounted shower heads will track people's movements.

"[13] All services at Cambridge Heath are operated as part of the Weaver line of the London Overground using Class 710 EMUs.