On 7 August 1903 a meeting was held under the presidency of the late H. Shepherd, Esq., at which it was decided to form a rugby club at Cambuslang.

During this period, the club progressed to the extent of running two teams, raising funds, and building a small clubhouse.

All through this period, the club took a leading place in sport in the West of Scotland and was a member of the Old Football Union.

In the season 1921–22 and again in 1922–23, Cambuslang were Western District Champions, as a result of which they were offered a match against a West of Scotland Senior Select XV that contained one or two internationalists.

In fact, all through the interwar period, the club had developed more and more into an organization of the young people of the district and was to be found in the lead in many local events.

Its pre-war Saturday evening dances held in the Institute were ever popular, and its annual whist drives and sales of work were looked forward to universally.

During the war, Coats Park was used by Clyde Paper Mill for storing huge bales of esparto grass.

In 1953 a memorable dinner was held in the former Cambuslang Golf Clubhouse in Clydeford Road to celebrate 50 years of the club.

For some obscure design reason there was an open roofed area which housed a unique urinal, composed of a length of ogee guttering with a household tap at one end.

The Whitlaw Burn which ran at the back of the club's pitches was piped in and the bing was bulldozed and grass sown.

It was felt that the clubs traditional strip of claret and amber horizontal stripes was too similar to that of Glasgow High School and West of Scotland so the present jersey based on an old established tie design was adopted.

The Railway Tavern – now Findlays, in Cambuslang Main Street, the Wooden Cask at Silverbanks, the Fairway in Rutherglen, and the Cambus Court all received patronage.

Mining subsidence caused a drop in one area of 16 ft between 1946 and 1962 and standing on the center spot of the 2nd XV pitch it was impossible to see the crossbar of one of the goals.

His work was so poor that then President, Bobby Robertson, a Civil Engineer by profession, categorically refused to accept it.

The greatest success of the club up to this time was in the 1991–92 season when, in successive cup games, it defeated Kilmarnock, West of Scotland, and, its best result ever, Stewarts Melville, who were beaten despite fielding Douglas Wyllie a Scottish international and Finlay Calder a former Scottish and British Lions captain.

After a disappointing season, 1998–99, which saw Cambuslang relegated to National League Division 3, there has been a distinct upturn in fortunes for the club.