Built as Stalag II-A Neubrandenburg in 1939, it was extended by the officer camp Oflag II-E in 1940 (renamed Oflag-67, 1944).
In late summer 1941 Soviet prisoners from Operation Barbarossa arrived and were placed in a separate enclosure built south of the main camp.
From November 1944 to early January 1945 American soldiers captured in various operations during the Allied drive eastward arrived.
From February to April 1945 Neubrandenburg was a waypoint in the forced march westward of Allied prisoners from POW camps further east.
In the middle of April most of the prisoners in the camp and in the outlying Arbeitskommandos were marched westward ahead of the advancing Red Army.
The largest was Teterow, several miles west of Neubrandenburg, which held about 175 prisoners living in a multi-storey brick building.
After some time the officers were separated out and placed initially in the garages of the adjoining German Army armoured division.
About 15,000 men, women and children were interned in the camp, and 5,000 of them died, primarily of starvation and disease.