The first white settler to own land in the village was Calvin G. Hill, a native of New York, who bought 400 acres (1.6 km2) in 1834 on both sides of the Thornapple River.

The name Middleville was at first given to a post office on the stage coach line between Grand Rapids and Kalamazoo.

The post office was located at the house of Benjamin S. Dibble in section 2 in northeast Yankee Springs Township.

Dibble had agreed to accept the post office at the request of U.S. Representative Lucius Lyon, of Kent County.

[6][7][8] The location of the original Indian village is NNE a few hundred yards of the present day intersection where Norris Rd.

[9] Several West Michigan television stations have their transmitting towers in the Middleville area, including: WOOD-TV and WXMI.

They are: Middleville is 5 miles (8.0 km) from one end of the developed part of the Paul Henry-Thornapple Trail.

A three-mile (5 km) section is already blacktopped, and is popular with roller-bladers, bikers, runners and walkers.

The SGAs also offer turkey, grouse, squirrel, goose, duck, rabbit and raccoon hunting opportunities.

The Thornapple-Kellogg Middle School hosts the National 24-Hour Challenge bicycling event, held annually on Father's Day weekend.

Camp Manitou-Lin is located in Middleville, Michigan, United States, approximately 30 miles south of Grand Rapids.

From 2011 onwards the camp has run a free program for the children of wounded, disabled or killed military personnel.