It is known for Campbellsville University, Taylor Regional Hospital health care system, its historic downtown, and the proximity to Green River Lake State Park.

Campbell owned a gristmill and a tavern and began selling lots in Campbellsville in 1814.

The city agreed to sell the public square to the county for one dollar so that a courthouse could be built.

The Campbellsville Historic Commercial District includes several blocks of Main Street.

The city's first courthouse was burned by Confederate cavalry in 1864 because the Union Army was using it for barracks.

A fourth courthouse referred to as the Justice Center building was built on Main Street (along with a new adjoining county jail) in 2008.

The project removed several old commercial buildings from the 300 block of East Main Street.

The climate is characterized by hot, humid summers and generally mild to cool winters.

The university's operations directly employ and support over 13.26% of all jobs in Taylor County, Kentucky.

The park's initial tenant is an automotive components manufacturer, the INFAC Corporation.

In the 20th century, Campbellsville was a regional center of industry (agriculture, lumber, textiles, milling, automotive, distribution, oil and gas, light manufacturing, education, healthcare, and tourism).

For decades, employment in the area was dominated by a large textile plant, formerly Union Underwear and since Fruit of the Loom.

It closed in 1998 due to cost cutting measures, with production moving to Latin America.

[15] In 1969, the booming petroleum business was shut down because of environmental concerns of excess salt water disposal.

During city council meetings held monthly, the mayor presides and all thirteen members have voting rights.

RTEC provides public transit service that serves a 13-county area in southeast Kentucky.