The School also has a Gallery building and the Tesseneer complex (which has a printing press room and a classroom), that were once houses.

The university offers programs in Louisville, Somerset, Harrodsburg and Elizabethtown in addition to the main campus.

The Doctor of Chiropractic program is designed to provide graduate students with a comprehensive education in spinal health, musculoskeletal care, and holistic patient management.

Emphasizing evidence-based practices, the curriculum integrates rigorous academic coursework, hands-on clinical training, and research opportunities.

With a focus on fostering a culture of care, the school prepares graduates to become compassionate, skilled healthcare providers who contribute to improving community wellness.

The university is a member of the National Association of Intercollegiate Athletics (NAIA), primarily competing in the Mid-South Conference (MSC) since the 1995–96 academic year.

They are also a member of the National Christian College Athletic Association (NCCAA), primarily competing as an independent in the Mid-East Region of the Division I level.

Campbellsville competes in 30 intercollegiate varsity sports: Men's sports include baseball, basketball, bowling, cross country, football, golf, soccer, swimming, tennis, track & field, volleyball and wrestling; while women's sports include basketball, bowling, cross country, dance, flag football, golf, soccer, softball, swimming, tennis, track & field, volleyball and wrestling; and co-ed sports include archery, bass fishing, kayak bass fishing, cheerleading and eSports.

Lady Tiger Volleyball advanced to the 2008 NCCAA Final Four but lost to Dallas Baptist to conclude the season with a record of 35–11.

[14] CU returned to the NCCAA Volleyball Tournament in 2009, sweeping through the field to win the school's first team national championship in Kissimmee, Florida.

The university is a member of the United States Collegiate Athletic Association (USCAA), primarily competing as an Independent since the 2018–19 academic year.

They are also a member of the National Christian College Athletic Association (NCCAA), primarily competing as an independent in the Mid-East Region of the Division II level.

The Pioneers men's basketball team won the 2022 NCCAA Division II National Championship by defeating Crown College.