[1] According to the National Biodiversity Information System of Comisión Nacional para el Conocimiento y Uso de la Biodiversidad (CONABIO) in Campo Verde Flora and Fauna Protection Area there are over 255 plant and animal species from which 32 are in at risk category and 4 are exotics.

[4] Native mammals include American black bear (Ursus americanus), white-tailed deer (Odocoileus virginianus), puma (Puma concolor), Mexican big-eared bat (Corynorhinus mexicanus), Zacatecan deer mouse (Peromyscus difficilis), and Chihuahuan mouse (Peromyscus polius).

[4] Native birds include the Gould's wild turkey (Meleagris gallopavo mexicanus), golden eagle (Aquila chrysaetos) eared quetzal (Euptilotis neoxenus), thick-billed parrot (Rhynchopsitta pachyrhyncha), Aztec thrush (Ridgwayia pinicola), and Bewick's wren (Thryomanes bewickii).

[4] Native reptiles include the Mexican Plateau horned lizard (Phrynosoma orbiculare), northern pigmy skink (Plestiodon parviauriculatus), Chihuahuan skink (Plestiodon multilineatus), Mexican wandering garter snake (Thamnophis errans), and blackbelly garter snake (Thamnophis melanogaster).

[4] Native amphibians include the Tarahumara salamander (Ambystoma rosaceum), Mexican tiger salamander (Ambystoma velasci), Lemos-Espinal's leopard frog (Lithobates lemosespinali), Tarahumara frog (Lithobates tarahumarae), pine toad (Incilius occidentalis), plateau toad (Anaxyrus compactilis), and Mexican Madre toad (Anaxyrus mexicanus),[4] The area was decreed a forest reserve and wildlife refuge by President Lázaro Cárdenas in 1938.