Menispermum canadense, the Canadian moonseed, common moonseed, or yellow parilla, is a flowering plant in the family Menispermaceae, native to eastern North America, from southern Canada south to northern Florida, and from the Atlantic coast west to Manitoba and Texas.

It is a woody climbing vine growing to 6 metres (20 feet) tall.

The seed inside the berry resembles a crescent moon, and is responsible for the common name.

The root is a rhizome, so one specimen can form colonies of genetically identical plants.

[6] The Cherokee used moonseed as a laxative, and as a gynecological and venereal aid.