It was the first new television station in Mexico City since 1968, when channels 8 (XHTM, operated by Televisión Independiente de México) and 13 (XHDF-TV, which was nationalized in 1972) went on the air.

The station became known as Cine Canal 22, changing its callsign to XEIMT-TV, and introduced a programming schedule focused on movies.

As it was the first UHF station in the area, not all televisions could receive it, and its transmitter in Ajusco did not offer enough power or height to cover the city.

In March 1993, XEIMT returned to air with test signals from a new transmitter location, Cerro del Chiquihuite, which offered vastly improved coverage of the Mexico City area.

On June 23, 1993, with an address from President Carlos Salinas de Gortari, Canal 22 officially reopened under the auspices of Conaculta (the National Council for Culture and the Arts) and concessionaire Televisión Metropolitana.

In 2001, Enrique Strauss, a highly regarded figure in the production of cultural television in Mexico, became the new director general of the station.

The block, named Clic Clac, features mostly European animated and live-action series as well as cultural segments produced by the channel.

With the creation of the Organismo Promotor de Medios Audiovisuales (now known as the Sistema Público de Radiodifusión del Estado Mexicano), a government agency formerly under the auspices of the Secretariat of the Interior, Channel 22's coverage has been significantly expanded outside Mexico City via the SPR transmitter network, which has a geographical coverage of 66%.