Canalou is a city in New Madrid County, Missouri, United States.

[6] According to the United States Census Bureau, the city has a total area of 0.20 square miles (0.52 km2), all land.

There were 121 housing units at an average density of 605.0 per square mile (233.6/km2).

22.8% of all households were made up of individuals, and 10.5% had someone living alone who was 65 years of age or older.

The racial makeup of the city was 95.11% White, 3.74% African American, 0.29% Asian, and 0.86% from two or more races.

21.6% of all households were made up of individuals, and 12.0% had someone living alone who was 65 years of age or older.

The Public Radio International documentary show This American Life aired a half-hour segment featuring Canalou, titled "You Can't Go Home Again," as part of its April 9, 1999 "Do-Gooders" episode.