The Canandaigua Outlet is a main tributary which feeds the Erie Canal and Clyde River in Wayne County, New York, United States.

It begins at Canandaigua Lake in nearby Ontario County and flows approximately 34 miles (55 km) north before emptying into the Erie Canal in the hamlet of Lyons.

Following the New York State Thruway, the outlet heads east through the town of Manchester passing just north of the village of Clifton Springs and into the community of Gypsum.

[7] The annual Wild Water Derby takes place every April in Shortsville and Manchester for class II & III whitewater canoeing, kayaking and rafting.

[4][8] Cheerful Valley Campground is also located near the Canandaigua Outlet on NY Route 14 in the town of Phelps between Lyons and Geneva.