It features the Avengers team of Marvel Comics characters in a side-scrolling brawling and shooting adventure to defeat the evil Red Skull.

Along with battling generic enemies, players also face Klaw, the Living Laser, Whirlwind, a Sentinel, Wizard, the Grim Reaper, the Mandarin, Juggernaut, Ultron, The Controller, the assassin Crossbones and finally the Red Skull himself.

Data East released a home version of the game in North America for the Sega Genesis co-developed with ISCO/Opera House.

The only playable characters in this version are Captain America and Hawkeye; their mission is to save the Vision and Iron Man from Mandarin, then defeat the Red Skull.

One page of Matt Fraction and David Aja's run of Hawkeye comics directly lifts from the arcade game's artwork.

[12] In Japan, Game Machine listed Captain America and The Avengers on their January 1, 1992 issue as being the fourth most-successful table arcade unit of the month.