Carbadox is indicated for control of swine dysentery (vibrionic dysentery, bloody scours, or hemorrhagic dysentery); control of bacterial swine enteritis (salmonellosis or necrotic enteritis caused by Salmonella enterica); aid in the prevention of migration and establishment of large roundworm (Ascaris suum) infections; aid in the prevention of establishment of nodular worm (Oesophagostomum) infections.

[1] In animal models, carbadox has been shown to be carcinogenic[citation needed] and to induce birth defects.

[2] The Food and Drug Administration's Center for Veterinary Medicine has questioned the safety in light of its possible carcinogenicity.

[3] Carbadox is approved in the United States only for use in swine and may not be used within 42 days of slaughter or used in pregnant animals.

[1] In 2016, the United States Food and Drug Administration moved to ban its use in pork, citing a potential cancer risk to humans.