Carbromal

Carbromal is a hypnotic/sedative originally synthesized in 1909 by Bayer and subsequently marketed as Adalin.

[1][2] The drug was later sold by Parke-Davis in combination with pentobarbital, under the name Carbrital.

The Hell-Volhard-Zelinsky reaction converts this to 2-Bromo-2-Ethylbutyryl Bromide [26074-53-3] (3).

Reaction with urea with affords carbromal (4).

This sedative-related article is a stub.

Skeletal formula of carbromal
Skeletal formula of carbromal
Carbromal synthesis: [ 2 ] [ 4 ] [ 5 ] Literature: [ 6 ] [ 7 ]