Cardinal Lemoine (French pronunciation: [kaʁdinal ləmwan]) is a station on Line 10 of the Paris Métro.

Line 10 was deviated from its old route east of Maubert – Mutualité to the new station of Jussieu.

Cardinal Lemoine was built at the southeastern end of the old route under Rue Monge.

It is named after the Rue du Cardinal Lemoine, named after Cardinal Jean Lemoine (1250–1313), a papal legate of Pope Boniface VIII to Philip IV the Fair.

As part of the RATP's "Metro Renewal" programme, the station's corridors and platform lighting were renovated and inaugurated on 20 November 2006.