The editors-in-chief are William H. Frishman (New York Medical College) and Patrick T. O'Gara (Brigham & Women's Hospital).

The aim of the journal is to publish comprehensive, and authoritative reviews for practicing clinicians.

Topical coverage includes diagnosis, clinical courses, prevention, and treatment of cardiovascular disorders.

Publishing formats are invited reviews, unsolicited critiques, and unsolicited comprehensive analysis, all pertaining to cardiovascular disease and treatment.

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