He was the Republican nominee for the United States House of Representatives in Florida's 18th congressional district in 2014[1] but was defeated by Patrick Murphy.

In 2014, at the age of 70, Domino obtained a Juris Doctor degree from Nova Southeastern University's Shepard Broad College of Law.

He won a six-way Republican primary in August 2014, and faced incumbent Democrat Patrick Murphy in the general election.

[6] In 2016, Domino ran again for the Republican nomination for the 18th District seat, which was being vacated by Murphy, but lost the August 30, 2016, placing fourth with 13% of the vote in a six-way race that was won by Brian Mast.

He has served on the board of directors of the Seminole Boosters, the American Cancer Society, the Palm Beach Economic Council, and Easter Seals Florida.