Current research at the IGB explores the genomic bases of a wide range of phenomena, including the progression of cancer, the ecological impact of global change, tissue and organ growth, and the diversity of animal behavior.

[citation needed] The IGB was initially led by Harris Lewin, then a professor in the Department of Animal Sciences at the University of Illinois.

Lewin served as the founding director until 2011, when he accepted the position of Research Vice Chancellor at University of California, Davis.

[5] The IGB houses approximately 130 faculty and 600 graduate students, postdoctoral fellows, and research personnel.

[9] Inside, each Research Theme has a large, open plan laboratory space and additional work rooms and office and meeting area.