Carl Schmitz-Pleis, originally Karl Schmitz (21 September 1877, Hennef – 1943, Düsseldorf) was a German painter.
He studied at the Kunstakademie Düsseldorf with Johann Peter Theodor Janssen, Eduard von Gebhardt and Claus Meyer [de].
At first, he signed his works with his birth name, but later adopted "Carl Schmitz-Pleis" as a more distinctive artistic pseudonym.
In his later years, he rarely left Düsseldorf; dying unmarried, childless, and apparently forgotten, in 1943.
In retrospect, he can be considered the most important German representative of Neo-Impressionism and Post-Impressionism alongside Paul Baum.