After graduating from a conservatory in Santa Cruz de Tenerife and embarking on an acting career, she subsequently transitioned to politics, serving as a member of the Assembly of Madrid between 2011 and 2021.

She studied drama at the Conservatory of Music and Dramatic Arts in Santa Cruz de Tenerife before leaving her hometown in 1977 due to experiencing transphobia, which she has attributed to its rural location.

That same year, Antonelli commenced her activism when she called for an end to the 1970 Law on dangerousness and social rehabilitation, which had been implemented during the Francoist dictatorship and criminalised homosexuality and targeted the LGBT community.

[5] In 2004, the PSOE won the general election on a platform that supported same-sex marriage and gender recognition for trans people, but the latter legislation was delayed passing through the Congress of Deputies.

[4] She subsequently acted as a spokesperson for the Federación Estatal de Lesbianas, Gays, Transexuales y Bisexuales and gave talks on transgender rights both in Spain and also internationally, including in Venezuela, Chile, Mexico, Cuba, Colombia and Argentina.