[5] In November 2015, it was announced that the University of Illinois and Carle Foundation Hospital had signed a 10-year research affiliation agreement with the intent to encourage and enable new biomedical advances at the newly formed college of medicine.
The University of Illinois College of Medicine had a regional campus in Urbana-Champaign for over 40 years, and was the primary site for the school's MSTP program.
As of January 2019, the college only accepts applications from United States citizens or permanent residents who will have completed a bachelor's, master's or doctorate degree, in any field, from a U.S. or Canadian accredited college or university prior to enrollment.
Carle Illinois does not conduct interviews as part of the application process, as is traditional for some other medical schools.
[9] The inaugural class of the Carle Illinois College of Medicine consisted of a group of 32 candidates,[10] with 16 men and 16 women, averaging approximately 26 years of age.
All of the students of the college's inaugural class received full, four-year privately funded scholarships, valued at approximately $250,000 each.
The external Research Advisory Board is composed of professors and doctors from colleges, universities and hospitals all across the country, while the internal board is composed of professors from various colleges at the University of Illinois, directors and other individuals from research labs across campus, and doctors from Carle Foundation Hospital.
[12] The Health Maker Lab hosts an annual “Health Make-a-thon" competition in which students, community members, and citizen scientists submit their ideas on how to improve the human condition.