Carlisle Hubbard Humelsine (1915 – January 25, 1989)[1] was an American diplomat and military officer who served as the Assistant Secretary of State for Administration from 1950 to 1953.

[2] During World War II, he reached the rank of full colonel at 29, earning the Distinguished Service Medal and the Bronze Star.

While at the State Department, Humelsine was instrumental in orchestrating the persecution of suspected homosexual employees known as the Lavender scare.

In June 1950, he wrote a three-page memo to Under Secretary James E. Webb titled "Problem of Homosexuals and Sex Perverts in the Department of State" which described how the State Department, under the direction of then Assistant Secretary for Administration John Peurifoy, began investigating and firing suspected homosexuals in 1947.

[4] Humelsine then served as the State Department's spokesperson throughout the Senate investigation,[5] which culminated in the subcommittee's report declaring homosexuals to be unsuitable for government employment.