Carlo of Napoli and Sicilia (Italian: Carlo Tito Francesco Giuseppe; 4 January 1775 – 17 December 1778) was Duke of Calabria as heir to Napoli and Sicilia.

Born at the Caserta Palace near Naples, he was known as the Duke of Calabria at birth as the heir apparent to his father's throne.

His mother was a daughter of Empress Maria Theresa and thus sister of Marie Antoinette.

A member of the House of Bourbon, he was a prince of Naples and Sicily by birth.

His birth allowed his mother to have a place in the Council of State, pursuant to his parents' marriage contract.