[1] The Carlo Besta Neurological Institute was founded in 1918.

[2] In 1981 the Italian government designated it as an Institute of Research and Treatment (IRCCS).

[2] The Carlo Besta Neurological Institute is a member of EuroBioBank's biobank program.

[citation needed] Here is active the first, and the most important, neurosurgical simulation center in Europe and the most equipped in the world (Besta NeuroSim) that enable the neurosurgeons residents to practice before to operate on a person.

[3] The other activities regard neurological disorders, brain cancer, neuromuscular disorders, vascular, functional and oncological neurosurgery and pediatric neurology and neurosurgery.