His activity in the cathedral of Milan - the only one certified so far - was remembered in the Annals only starting from 1631, just after the death of Gianandrea.
The execution of an Angel started by his father was entrusted to Biffi, for which he still received payments in 1638, but which would then be finished by Vismara.
The angels are also recognized in the cathedral in the niches of the internal piers on the sides of the Main Cross.
More interesting must have been the activity of Biffi as an engraver: the portrait of Francesco Gabrielli, signed and dated 1633, was cited with praise by Bartsch; we still know a print with four caricature heads, signed "Biffius" and by Le Blanc referring to it, and four plates he drew and engraved by Cesare Laurenti, with allegorical fights, published in the book Amore and Glory.
In 1691 his sons Filippo and Giuseppe dedicated a funeral monument to him in the church of St. Antonio Abate.