Carlo Caione (born 18 February 1973 in L'Aquila) is a former Italian rugby union player and a current sports director.

Caione first played for L'Aquila Rugby, where he had his debut for the first team in 1990/91, aged only 17 years old.

Caione then would play for Rugby Roma Olimpic, from 1998/99 to 2002/03, winning the Cup of Italy in 1998/99 and the Italian Championship in 1999/2000.

He returned to L'Aquila Rugby, where he would finish his career in 2004/05, aged 32 years old, due to a serious injury.

The highest point of his international career was the conquest of the FIRA Cup for the 1995/1997 season.