Although his compositions include a wide variety of genres and instrumentation choices, he is best known for his works for solo guitar, and particularly the Koyunbaba suite.

His works explore and borrow from a wide variety of national traditions, including Turkish, Indian, Brazilian, and many more.

One of the defining characteristics of Domeniconi's music is its exploration of various national styles, which include Turkish (Koyunbaba, Variations on an Anatolian Folk Song, Sonatina turca, Oyun),[5] Indian (Gita, Dhvani), various South American styles (Suite Sud Americana, Vidala, Sonido), and many others.

The liner notes to a recording made by Domeniconi in 1991 for a Turkish record label state that the work is a suite pastorale, describing "the natural beauty of a little bay" overlooking the Aegean Sea, where the saint was said to live centuries ago.

[8] Educational music has been a particularly important field for Domeniconi, as numerous works he composed for young players attest, such as Klangbilder (Sound Pictures), 24 Preludes, and Eine kleine Storchsuite.