In 1971 Marrale co-founded with keyboardist Piero Cassano and bassist Aldo Stellita the progressive rock band Jet, in which he performed as guitarist and main vocalist.
In 1975, Jet expanded their line-up with the addition of vocalist Antonella Ruggiero and drummer Giancarlo Golzi and changed their name to Matia Bazar.
Marrale co-wrote many of the band's songs and performed vocals duties, duetting with Ruggiero in several early hits of the group, such as Stasera...che sera!
After Ruggiero's departure from Matia Bazar in 1989, Marrale continued his role as feature vocalist with the band's new lead singer Laura Valente.
Marrale also wrote songs for artists like Irene Cara, Miguel Bosé, Mina, Pet Shop Boys, Queensrÿche.