Carlo Perosi (18 December 1868 – 22 February 1930) was an Italian Cardinal of the Roman Catholic Church who served as Secretary of the Sacred Consistorial Congregation from 1928 until his death, and was elevated to the cardinalate in 1926.

Upon returning to Tortona, Perosi undertook his pastoral ministry, also serving as a diocesan official and professor and vice-rector at its seminary.

Elevated to the College of Cardinals before receiving his episcopal consecration, Perosi was created Cardinal-Deacon of S. Eustachio by Pope Pius XI in the consistory of 21 June 1926.

As Secretary, Perosi was effectively the head of that dicastery, as the Pope held the nominal title of Prefect at that time.

Lorenzo Perosi dedicated the score of his oratorio Il sogno interpretato to the memory of his brother Carlo.