Active during the late Baroque and early Classical music periods, Zuccari worked mainly in Milan, Olomouc, and London.
Immediately afterward, he spent years traveling Europe to build his fame as a virtuoso, serving for a time as a Kapellmeister before eventually settling in Milan.
At age 43, he published his masterpiece Sonate a Violino, e Basso ò Cembalo, Opera Prima.
As a violinist, Zuccari focused on intricate musical ornamentation for sonatas that relied heavily on his expertise.
His sonatas emphasized the history of music with authentic sounds, as opposed to cantatas, which were generally sung.