Carlos Freile Zaldumbide (18 May 1851 – 28 August 1928) was an Ecuadorian politician, who served twice as acting President of Ecuador and one term as Vice President of Ecuador.

[citation needed] Freile was a wealthy landowner who pioneered the raising of Holstein livestock in Ecuador.

[citation needed] He served as vice president to President Eloy Alfaro Delgado from 31 August 1899 to 31 August 1903.

After 21 days in office, Freile was replaced by the newly elected President Emilio Estrada on 1 September 1911.

Estrada died three months later, on 21 December 1911, and Freile again served as acting president until 6 March 1912 when he was succeeded by Francisco Andrade Marín.