Depth, Count Hypno, and Jane Reaction) have sent KnowBots (SynicBot, HALieBot, Pure-EBot, BruiserBot, DimBot, and Touchy-FezlyBot) to steal the world of its data and information from various texts.

At the beginning of each mission, Chase Devineaux, the ACME Detective Agency's top agent will describes the suspect and the vital stolen knowledge.

[18] In a review of a package entitled Adventure Workshop: 4th-6th Grade which featured the games The ClueFinders Reading Adventures Ages 9-12, Carmen Sandiego's ThinkQuick Challenge, and Super Solvers Mission: T.H.I.N.K., Hilary Williams of AllGame said that it is "one of those rare compilations where all of the included titles are superb", adding that ThinkQuick was "another great [Carmen] game that will interest older kids due to its international espionage theme" and that the game "retains the educational value of previous titles in the series, without losing entertainment value".

[20] SuperKids praised the "superb graphics", "intricate storyline", and gameplay that would "amaze and delight" Carmen Sandiego fans, though it may prove tiresome for those who had become tired of the quiz-based gaming genre.

[27] The Cincinnati Enquirer noted that this game saw a costume change from Carmen Sandiego's iconic red dress to a black catsuit.

[29] In a negative analysis, Robin Ray of the Boston Herald commented that ThinkQuick was part of a growing trend of gaming franchises in which previous titles which "could wholeheartedly [be] recommend[ed]", "[were not] a complete waste of time", and "[were] near-perfect combination of fun and learning" contrasted greatly with the new releases which instead "cause...slow burn".

[30] Home Computer Buying Guide said the game had a weaker and less interesting theme than previous Carmen Sandiego titles.

[31] Anne Sushko of The Book Report recommended the game as "well developed and of high interest", though noted that it was not compatible with Windows NT.