A product of the Northampton Town and Aston Villa academies, Chukwuemeka made his debut for the latter club's first team in 2021, before signing for Chelsea in 2022.

[7] Chukwuemeka made his senior debut for the team on 19 May 2021 in a 2–1 away victory over Tottenham Hotspur, hitting the post within minutes of entering the game.

[9] The following day, Chukwuemeka was part of the Aston Villa U18s squad that won the FA Youth Cup, beating Liverpool U18s 2–1 in the final.

[11] On 2 August 2022, Aston Villa and Chelsea confirmed that the clubs had reached an agreement for the permanent transfer of Chukwuemeka, subject to the player agreeing personal terms and undergoing a medical.

[14][15] On 20 August 2023, Chukwuemeka scored his first senior goal in a 3–1 loss to West Ham United, later in the same match he was substituted after suffering a knee injury.

[16] On 3 February 2025, Bundesliga club Borussia Dortmund signed Chukwuemeka on loan until the end of the season, with an option to make the move permanent.