It was part of the agency's Vessel Sanitation Program, whose purpose is to prevent the transmission and spread of gastrointestinal disease.

[10] On September 4, 2018, due to heavy rain and flooding in Galveston, Texas, Carnival Valor's departure was delayed.

[16] On August 3, 2017, the ship contacted the Houston-Galveston Coast Guard station and requested assistance for a woman who was injured from a fall.

He was picked up by a Coast Guard MH-65 218 miles (351 km) south of Southwest Pass, Louisiana and transported to New Orleans.

[20] On February 16, 2022, a 32-year-old woman fell overboard while the vessel was around 150 miles (240 km) from the coast of Louisiana when heading to New Orleans after a port call in Cozumel, Mexico.

[22] During the coronavirus pandemic, the CDC reported, as early as April 22, 2020, that at least one person tested positive for SARS-CoV-2 after disembarking.