In 2008, she was elected as a municipal councillor of Noyon and became, in 2010, first deputy mayor of the town.

From 2017 until 2019, she served as one of six vice-presidents of the National Assembly, under the leadership of president Richard Ferrand.

[4] She lost her seat in the second round of the 2022 French legislative election to National Rally candidate Michel Guiniot.

In July 2019, Bureau-Bonnard voted in favour of the French ratification of the European Union’s Comprehensive Economic and Trade Agreement (CETA) with Canada.

[5] In 2019, Bureau-Bonnard's office in Noyon was vandalized during anti-government protests of the Yellow vests movement.