It was the home of the USC men's and women's basketball teams from 1968 to 2002, as well as Columbia's main events venue until 2002, when the Colonial Life Arena, opened a block away on Greene Street.

The facility was unique at the time, being built to serve not only as an entertainment venue but also as a home to university classrooms with classes held in the lower levels.

Until 2002, when Greenville's Bon Secours Wellness Arena served as host, it was the only time the tournament was played in South Carolina.

That same year, Elvis Presley held a concert at the Coliseum, his last time performing in South Carolina.

In the fall of 2014, 3,000 seats were removed and the arena floor was converted into two practice courts for the Gamecock men's and women's teams.