She began her career in the media in 2005 when she ended up as a finalist in the third edition of the Ghanaian reality TV pageant Miss Malaika Ghana.

She was the first anglophone African and Ghanaian to win the award for Best Presenter at the Stars Integration of Culture of Africa festival and competition held in Benin.

[1][2] Sampson's career began as a contestant in the third edition of the TV reality show, Miss Malaika Ghana, in 2005.

[9][10] After two years with Citi FM, Sampson joined YFM Ghana as a presenter for the weekly show, Shout on Y.

[11][12][13] In 2017, Sampson and Ghanaian rapper, Kofi Kinaata, were brand ambassadors for beverage company Guinness Ghana.