The daughter of the Irish engraver James Watson, she was born in London in 1760 or 1761, and studied under her father, who worked in mezzotint.
[2] She came to prominence as an engraver at about the same time as women began to make up a significant proportion print consumers.
[3] Her career began to wind down after 1810 due to ill health, and she died at Pimlico on 10 June 1814.
In 1784 she engraved a portrait of Prince William of Gloucester, after Joshua Reynolds, and in 1785 a pair of small plates of the Princesses Sophia and Mary, after John Hoppner, which she dedicated to Queen Charlotte.
She engraved portraits of:[1] Other works were:[1] Watson also executed a set of aquatints of the Progress of Female Virtue and Female Dissipation, from designs by Maria Cosway.