[6] She graduated from Swarthmore in 1952; in the yearbook, Halcyon, the phrase "I left the n off on purpose... caroly" is printed with her picture.

[10] She appeared in the Broadway show The Next President in 1958, danced in a Brooklyn lecture-demonstration in 1963,[11] and worked on a Pickwick Puppet Theater production in Boston in 1970.

[13] She designed, built, and performed characters for Sesame Street,[14] including the Yip-Yips and an early version of Elmo, from its launch in 1969 until her retirement in 2012.

She also worked on The Muppet Show (1976–1981), Emmet Otter's Jug-Band Christmas (1977), and Fraggle Rock (1983–1987), and Put Down the Duckie (1988).

[19] In 2020, Wilcox appeared with fellow Jim Henson colleagues Bonnie Erickson and Rollie Krewson in an online interview hosted by the Museum of the Moving Image.