Carryover effect

The carryover effect is a term used in clinical chemistry to describe the transfer of unwanted material from one container or mixture to another.

The significance of carry over is that even a small amount can lead to erroneous results.

The pipetting and washing systems in an automated analyzer are designed to continuously cycle between the aspiration of patient specimens and cleaning.

The pathological range of measurement could be of several order to reference interval(e.g., Sex hormone, Tumor marker, Troponin...etc.).

IUPAC made a recommendation in 1991[1] for the description and measurement of carryover effects in clinical chemistry.

Carryover illustration in a typical carryover study in automated analyzer