"[3] The entire firm and both of its divisions and their separate buildings were destroyed the night of November 9, 1872, in what has been called the Great Boston Fire of 1872.

The building's huge "Carter's Inks" electric sign faced the Charles River and was an area landmark for many years.

Richard Carter continued his father's commitment to research and development of inks, glues and related products.

Francis J. Honn invented the highlighting marker (under the trademark Hi-Liter) as the Vice President of Technology at Carter's in 1963.

[2] Samuel D. Wonders was followed by Nathan C. Hubley, Jr who retired as president in 1976 when the company was sold to Dennison.

[2] In the summer of 1984, the Thinking Machines Corporation (the market leader in parallel computing by then) moved its headquarters to top floors in the building.

[8] In 2004, the building was converted to include 130,000 square feet of lab space to accommodate acquisition by ViaCell, a cellular medicine research company later acquired by PerkinElmer.