Leake Central High School is a public school located at 704 Jordan Street in Carthage, Mississippi, United States.

Leake Central High School serves students enrolled in grades 9-12 and was built in 1961.

Webster Construction Company of Meridian built CHS.

Carthage High School along with Edinburg Attendance Center and Thomastown Attendance Center were consolidated for the 2011–2012 school year following a court order from the Department of Justice.

The gator mascot and school colors (orange, black, and white) were selected by the students.