The museum is a collaboration of specialists and volunteers who dedicated their talents and resources to preserve the threatened site of the ancient Mediterranean, Carthage.

It has undergone extensive restructuring in the 1990s, and has now been redesigned to accommodate new discoveries on the site of Carthage, especially the product of searches conducted as part of the international campaign of the UNESCO, from 1972-1995.

The museum contains items which reveal a distinct connection with the Levant steeped in Egyptian and in particular Greek culture, and the ties of Carthage with Sicily during the Hellenistic period.

[4] The amulets of Egyptian deities (Isis, Osiris, Horus, and Bès) indicates the importance of ties between the Phoenicians and the Ancient Egypt, the first retaining these cultural elements once they arrived in the Western Mediterranean.

There are also various items including razors made of bronze and richly decorated with cast patterns, illustrating Egyptian and Greek influences.

The terracotta perfume-burner in the form of the head of Ba'al Hammon was discovered in a sanctuary in the Salammbô quarter unearthed by Dr Louis Carton shortly after World War I.; at the same time diverse other cultural objects came to light, including representations of Demeter[8] The steles of the topheth are on the other the most important collection that is available.

Although stelae were reported in the early research on the site of Carthage, especially during searches of Pricot of Mary (1874), most of which ran with the Magenta 'in 1875, many of the most interesting parts are deposited in the museum after the discovery of the sanctuary in 1921 in addition to the most common steles sandstone's El Haouaria, steles later limestone subject most often varied scenery: ships, palm trees, elephants and even elements portraits strong Hellenistic influence.

Two foundation deposits containing mostly ceramics were discovered, one located at the base of a wall and the other called "hideout" was under the floor of a small vaulted room.

[10] The history of the Roman city of Carthage begins with a disaster, the will to destroy a rival dating from 146, which has some moving testimonies from the period on showcase.

Elements of the official Roman art were discovered on the Byrsa hill, including sculptures and bas reliefs depicting victory.

These excavated items have been interpreted as a commemoration of the victory over the Parthians in 166, during the reign of Marcus Aurelius and presented on a triumphal arch or monument portal.

A large number of funerary inscriptions discovered by Alfred Louis Delattre are displayed in the Carthage museum, found during his excavation of the main basilica.