The rapids were an important fishing site for Native Americans, who would catch salmon as they swam upriver to spawn.
They also posed a major obstacle to the development of the Oregon Trail; initially, pioneers would gather at The Dalles to await small boats to carry them to the Willamette Valley; in 1845, Sam Barlow and his associates built a road around the south side of Mount Hood, which allowed travelers along the Trail to bypass the rapids on the last leg of their journeys.
... a few men were absolutely necessary at any rate to guard our baggage from the War-clel-lars who crowded about our camp in considerable numbers.
[citation needed] Although more diplomatic approaches eventually prevailed, a malaria outbreak in the 1830s so reduced the populations of the Cascade and other Indian tribes, that they ceased to be a powerful force along the river.
Steamboats could not go upriver through the rapids, and could be brought downriver only at great risk, although this was done a number of times by highly skilled captains.