Casscoe (also Cassco or Cass Coe) is an unincorporated community in Arkansas County, Arkansas, United States.

[1] The community is located where Arkansas Highway 33 Spur diverges from Arkansas Highway 33.

[3] The climate in this area is characterized by hot, humid summers and generally mild to cool winters.

[4] Residents are in the Stuttgart School District.

[5][6] It operates Stuttgart High School.