Castelnuovo Belbo (Piedmontese: Castelneuv Belb) is a comune (municipality) in the Province of Asti in the Italian region Piedmont, located about 60 kilometres (37 mi) southeast of Turin and about 20 kilometres (12 mi) southeast of Asti.

Castelnuovo Belbo borders the following municipalities: Bergamasco, Bruno, Incisa Scapaccino, Mombaruzzo, and Nizza Monferrato.

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